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1

A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle specificity through staining of F-actin and DNA

Petter C. Endresen, Per S. Prytz, Jarle Aarbakke

Journal:

Cytometry Part A

Year:

1995

Language:

english

File:

PDF, 1.03 MB

english, 1995

2

Antipyrine and acetaminophen kinetics in the rat: Comparison of data based on blood samples from the cut tail and a cannulated femoral artery

Wenche M. Johannessen, Ingvald M. Tyssebotn, Jarle Aarbakke

Journal:

Journal of Pharmaceutical Sciences

Year:

1982

Language:

english

File:

PDF, 612 KB

english, 1982

3

Is there a gender difference in red blood cell thiopurine methyltransferase activity in healthy children?

Dr. Bjørg Klemetsdal, Trond Flægstad, Jarle Aarbakke

Journal:

Pediatric Blood & Cancer

Year:

1995

Language:

english

File:

PDF, 437 KB

english, 1995

4

Thiopurine methyltransferase activity in a Korean population sample of children*

Park-Hah, Jeong Ok, Klemetsdal, Bjørg, Lysaa, Roy, Choi, Kwang Hae, Aarbakke, Jarle

Journal:

Clinical Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 888 KB

english, 1996

5

Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms*

Otterness, Diane, Szumlanski, Carol, Lennard, Lynne, Klemetsdal, Bjørg, Aarbakke, Jarle, Park-Hah, Jeong Ok, Iven, Heiko, Schmiegelow, Kjeld, Branum, Earl, O'Brien, John, Weinshilboum, Richard

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 2.27 MB

english, 1997

6

Inhibition of 7-hydroxymethotrexate formation by amsacrine

Roy M. Bremnes, Eivind Smeland, Nils P. Willassen, Erik Wist, Jarle Aarbakke

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 835 KB

english, 1991

7

Interactions of vinblastine and vincristine with methotrexate transport in isolated rat hepatocytes

Eivind Smeland, Roy M. Bremnes, Atle Bessesen, Ragnhild Jæger, Jarle Aarbakke

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 596 KB

english, 1993

8

Maximum tolerated doses of methotrexate and 7-hydroxy-methotrexate in a model of acute toxicity in rats

Ole-Martin Fuskevåg, Christel Kristiansen, Sigurd Lindal, Jarle Aarbakke

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

9

High-dose 7-hydroxymethotrexate: Acute toxicity and lethality in a rat model

Eivind Smeland, Ole Martin Fuskevåg, Kirsten Nymann, John Sigurd Svendsen, Randi Olsen, Sigurd Lindal, Roy M. Bremnes, Jarle Aarbakke

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 5.05 MB

english, 1996

10

Methotrexate increases red blood cell concentrations of 6-methylmercaptopurine ribonucleotide in rats in vivo

Trude Giverhaug, Ole-Martin Fuskevaag, Jarle Aarbakke

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 141 KB

english, 1997

11

A Three Dimensional Model of Human Thiopurine Methyltransferase; Ligand Interactions and Structural Consequences of Naturally Occurring Mutations

Roy A. Lysaa, Ingebrigt Sylte, Jarle Aarbakke

Journal:

Journal of Molecular Modeling

Year:

1998

Language:

english

File:

PDF, 95 KB

english, 1998

12

Effects of 3-Deazaadenosine on Apoptosis-Related Gene Transcripts in HL-60 Cells

Thrina Loennechen, Ugo Moens, Hanne Kildalsen, Anders Andersen, Ole Petter Rekvig, Jarle Aarbakke

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1997

Language:

english

File:

PDF, 638 KB

english, 1997

13

The Role of Liver Alcohol Dehydrogenase Isoenzymes in the Oxidation of Glycolethers in Male and Female Rats

Lisbeth Aasmoe, Jan-Olof Winberg, Jarle Aarbakke

Journal:

Toxicology and Applied Pharmacology

Year:

1998

Language:

english

File:

PDF, 168 KB

english, 1998

14

The c-fos cAMP-response element: Regulation of gene expression by a β2-adrenergic agonist, serum and DNA methylation

Ugo Moens, Nanthakumar Subramaniam, Bjarne Johansen, Jarle Aarbakke

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1993

Language:

english

File:

PDF, 1.87 MB

english, 1993

15

Effect of the glutathione/glutathione disulfide redox couple on thiopurine methyltransferase

Roy A. Lysaaa, David J. Warren, Ingebrigt Sylte, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 1.47 MB

english, 2001

16

Sex-dependent induction of alcohol dehydrogenase activity in rats

Lisbeth Aasmoe, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

17

Synergistic increase in c-fos expression by simultaneous activation of the ras/raf/map kinase- and protein kinase A signaling pathways is mediated by the c-fos AP-1 and SRE sites

Ole Morten Seternes, Rita Sørensen, Bjarne Johansen, Thrina Loennechen, Jarle Aarbakke, Ugo Moens

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 476 KB

english, 1998

18

The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX)

Trude Giverhaug, Thrina Loennechen, Jarle Aarbakke

Journal:

General Pharmacology: The Vascular System

Year:

1999

Language:

english

File:

PDF, 109 KB

english, 1999

19

14C-Antipyrine as a Model Compound in the Study of Drug Oxidation and Enzyme Induction in Individual Surviving Rats

Olav M. Bakke, Michael Bending, Jarle Aarbakke, Donald S. Davies

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1974

Language:

english

File:

PDF, 340 KB

english, 1974

20

The Metabolism of Biphenyl. I. Metabolic Disposition of 14C–Biphenyl in the Rat

Trygve Meyer, Jarle Aarbakke, Ronald R. Scheline

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1976

Language:

english

File:

PDF, 386 KB

english, 1976

21

Metabolism of 14C-Antipyrine in Suspensions of Isolated Rat Liver Cells

Jarle Aarbakke, Atle Bessesen, Jarg Marland

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1977

Language:

english

File:

PDF, 522 KB

english, 1977

22

Disposition and Oxidative Metabolism of Antipyrine in the Rat

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1978

Language:

english

File:

PDF, 314 KB

english, 1978

23

An Improved Microscale HPLC Assay for Naproxen Plasma Levels

Audun Høylandskjær, Jarle Aarbakke

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1983

Language:

english

File:

PDF, 168 KB

english, 1983

24

A Simple HPLC Method for Measuring Metoclopramide in Serum

Lars Slørdal, Per S. Prytz, Ulf Aasebø, Jarle Aarbakke

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1986

Language:

english

File:

PDF, 243 KB

english, 1986

25

Biology and Pharmacology of Thiopurines

Aarbakke, Jarle

Journal:

Pediatric Hematology-Oncology

Year:

1995

Language:

english

File:

PDF, 550 KB

english, 1995

26

Binding of S-adenosylhomocysteine to various domains of the plasma membrane and to the endoplasmic reticulum from rat liver: Relation between binding and phospholipid methyltransferase activity

Jon-Sverre Schanche, Jarle Aarbakke, Per Magne Ueland, Gaut Gadeholt, Atle Bessesen, Tone Schanche

Journal:

Archives of Biochemistry and Biophysics

Year:

1983

Language:

english

File:

PDF, 570 KB

english, 1983

27

Interactions with the protein binding of 7-hydroxy-methotrexate in human serum in vitro

Lars Slørdal, Georg Sager, Ragnhild Jæger, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 514 KB

english, 1988

28

DNA-methylation in HL-60 cells treated with 3-deaza-(±)-aristeromycin and 3-deazaadenosine

Thrina Loennechen, Per S. Prytz, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 475 KB

english, 1989

29

Differential cell cycle perturbation by transmethylation inhibitors

Per S. Prytz, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 438 KB

english, 1990

30

The effect of vindesine on methotrexate hydroxylation in the rat

Roy M. Bremnes, Eivind Smeland, Lars Slørdal, Erik Wist, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 957 KB

english, 1991

31

Elevation of cyclic AMP levels in HL-60 cells accumulated in G1 or G2 by transmethylation inhibitors

Per S. Prytz, Berit E. Bang, Fetter C. Endresen, Conny Møller, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 655 KB

english, 1991

32

Is there an association between an increase in c-myc RNA steady state levels and c-myc methylation in HL-60 cells treated with 3-deaza-(±)-aristeromycin, an indirect inhibitor of methylation?

Thrina Loennechen, Inge W. Nilsen, Ugo Moens, Anders Andersen, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 919 KB

english, 1992

33

Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine

Petter C. Endresen, Tor J. Eide, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.35 MB

english, 1993

34

Thiopurine biology and pharmacology

Jarle Aarbakke, Gritta Janka-Schaub, Gertrude B. Elion

Journal:

Trends in Pharmacological Sciences

Year:

1997

Language:

english

File:

PDF, 693 KB

english, 1997

35

Lack of effect of fever on antipyrine oxidation in the rat

Jarle Aarbakke, Gaut Gadeholt, Harald Olsen

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 540 KB

english, 1978

36

Physiological cyclic AMP stimulation and oncogene mRNA levels in HL-60 cells

Ugo Moens, Berit E. Bang, Jarle Aarbakke

Journal:

Year:

1990

Language:

english

File:

PDF, 1.42 MB

english, 1990

37

Effect of anticancer drugs on drug metabolism

Lars Slørdal, Jarle Aarbakke

Journal:

Pharmacology & Therapeutics

Year:

1987

Language:

english

File:

PDF, 809 KB

english, 1987

38

Increased Concentrations of Methylated 6-Mercaptopurine Metabolites and 6-Thioguanine Nucleotides in Human Leukemic Cells In Vitro by Methotrexate

Trude Giverhaug, Thrina Loennechen, Jarle Aarbakke

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 552 KB

english, 1998

39

Gender difference in rat hepatic biotransformation of 2-methoxyethanol, 2-ethoxyethanol and 2-buthoxy-ethanol

Lisbeth Aasmoe, Jan-Olof Winberg, Jarle Aarbakke

Journal:

Toxicology Letters

Year:

1996

Language:

english

File:

PDF, 113 KB

english, 1996

40

Relationships of phytoplankton with certain environmental factors in the South Euboikos Gulf (Greece)

Slo̸rdal, Lars, Sager, Georg, Aarbakke, Jarle

Journal:

Deep Sea Research Part B. Oceanographic Literature Review

Year:

1987

Language:

english

File:

PDF, 98 KB

english, 1987

41

CARBON-MONOXIDE POISONING.

Slo̸rdal, Lars, Sager, Georg, Aarbakke, Jarle

Journal:

Year:

1923

Language:

english

File:

PDF, 404 KB

english, 1923

42

PHARMACOKINETIC INTERACTIONS WITH METHOTREXATE: IS 7-HYDROXY-METHOTREXATE THE CULPRIT?

Slo̸rdal, Lars, Sager, Georg, Aarbakke, Jarle

Journal:

Year:

1988

Language:

english

File:

PDF, 355 KB

english, 1988

43

LEUCOVORIN AND MAXIMUM TOLERATED DOSE TOXICITY OF METHOTREXATE IN RATS

Fuskevåg, Ole-Martin, Kristiansen, Christel, Lindal, Sigurd, Aarbakke, Jarle

Journal:

Pediatric Hematology-Oncology

Year:

2000

Language:

english

File:

PDF, 161 KB

english, 2000

44

High-Dose Methotrexate Therapy (6‐8 G/M 2 ) in Childhood Malignancies: Clinical Tolerability and Pharmacokinetics

Slørdal, Lars, Kolmannskog, Svein, Johan Moe, Peter, Prytz, Per S., Aarbakke, Jarle

Journal:

Pediatric Hematology-Oncology

Year:

1987

Language:

english

File:

PDF, 524 KB

english, 1987

45

Clinical Pharmacokinetics of Phenylbutazone

Dr Jarle Aarbakke

Journal:

Clinical Pharmacokinetics

Year:

1978

Language:

english

File:

PDF, 1001 KB

english, 1978

46

Therapeutic Drug Monitoring in Oncology

Aarbakke, Jarle

Journal:

Pediatric Hematology-Oncology

Year:

1990

Language:

english

File:

PDF, 109 KB

english, 1990

47

Pharmacokinetics of Methotrexate and 7-Hydroxy-Methotrexate after High-Dose (33.6 g/m 2 ) Methotrexate Therapy

Slørdal, Lars, Kolmannskog, Svein, Prytz, Per S., Moe, Peter Johan, Aarbakke, Jarle

Journal:

Pediatric Hematology-Oncology

Year:

1986

Language:

english

File:

PDF, 433 KB

english, 1986

48

Amiodarone Inhibits the Conversion of Thyroxine to Triiodothyronine in Isolated Rat Hepatocytes

AANDERUD, SYLVI, SUNDSFJORD, JOHAN, AARBAKKE, JARLE

Journal:

Year:

1984

Language:

english

File:

PDF, 567 KB

english, 1984

49

Effects of 3-Deazaadenosine, An Inducer of HL-60 Cell Differentiation, on Human Blood Cells in Vitro

Prytz, Per S., Loennechen, Thrina, Johansson, Per A., Larsen, Lars B., Slørdal, Lars, Aarbakke, Jarle

Journal:

Pediatric Hematology-Oncology

Year:

1989

Language:

english

File:

PDF, 493 KB

english, 1989

50

A Sensitive Gas Chromatographic Assay for Amitriptyline and Nortriptyline in Plasma

Hals, Petter-Arnt, Lundgren, Tor-Ivar, Aarbakke, Jarle

Journal:

Therapeutic Drug Monitoring

Year:

1982

File:

PDF, 353 KB

1982